ITT1012
ITT1012
- Catalog: ITT1012
- Gene/Protein: COL14A1
- Product Description: Immunotag™ COL14A1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | COL14A1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human Collagen XIV alpha1. AA range:71-120 |
Specificity | COL14A1 Polyclonal Antibody detects endogenous levels of COL14A1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | COL14A1 |
Accession No. | Q05707 Q80X19 |
Alternate Names | COL14A1; UND; Collagen alpha-1(XIV) chain; Undulin |
Description | collagen type XIV alpha 1 chain(COL14A1) Homo sapiens This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013], |
Protein Expression | Brain,Liver,Muscle,PNS,Testis, |
Subcellular Localization | extracellular region,proteinaceous extracellular matrix,collagen trimer,collagen type XIV trimer,extracellular space,endoplasmic reticulum lumen,extracellular matrix,extracellular exosome, |
Protein Function | function:Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.,PTM:Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates.,PTM:May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 2 VWFA domains.,similarity:Contains 8 fibronectin type-III domains.,subunit:Homotrimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |