ITT1184
ITT1184
- Catalog: ITT1184
- Gene/Protein: CNNM2
- Product Description: Immunotag™ Cyclin M2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cyclin M2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cyclin M2, at AA range: 540-620 |
| Specificity | Cyclin M2 Polyclonal Antibody detects endogenous levels of Cyclin M2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CNNM2 |
| Accession No. | Q9H8M5 Q3TWN3 Q5U2P1 |
| Alternate Names | CNNM2; ACDP2; Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2 |
| Description | cyclin and CBS domain divalent metal cation transport mediator 2(CNNM2) Homo sapiens This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011], |
| Protein Expression | B-cell,Colon,Placenta,Teratocarcinoma, |
| Subcellular Localization | integral component of membrane,basolateral plasma membrane, |
| Protein Function | function:Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,tissue specificity:Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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