ITT1201
ITT1201
- Catalog: ITT1201
- Gene/Protein: CYP26C1
- Product Description: Immunotag™ CYP26C1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CYP26C1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human CYP26C1. AA range:41-90 |
Specificity | CYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CYP26C1 |
Accession No. | Q6V0L0 |
Alternate Names | CYP26C1; Cytochrome P450 26C1 |
Description | cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Retinol metabolism, |
Protein Expression | Spleen, |
Subcellular Localization | endoplasmic reticulum membrane,integral component of membrane, |
Protein Function | cofactor:Heme group.,function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |