ITT1231
ITT1231
- Catalog: ITT1231
- Gene/Protein: CYP3A7
- Product Description: Immunotag™ CYP3A7 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CYP3A7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A7. AA range:231-280 |
| Specificity | CYP3A7 Polyclonal Antibody detects endogenous levels of CYP3A7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CYP3A7 |
| Accession No. | P24462 |
| Alternate Names | CYP3A7; Cytochrome P450 3A7; CYPIIIA7; Cytochrome P450-HFLA |
| Description | cytochrome P450 family 3 subfamily A member 7(CYP3A7) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015], |
| Cell Pathway/ Category | Steroid hormone biosynthesis,Linoleic acid metabolism,Retinol metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism,Drug metabolism, |
| Protein Expression | Fetal liver, |
| Subcellular Localization | endoplasmic reticulum membrane,organelle membrane, |
| Protein Function | catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.,induction:P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens.,online information:CYP3A7 alleles,similarity:Belongs to the cytochrome P450 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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