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ITT1297

ITT1297
ITT1297-2
ITT1297
ITT1297-2
  • Gene/Protein: GC
  • Product Description: Immunotag™ DBP Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT1297

Immunotag™ DBP Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein DBP
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Monkey
Host Species Rabbit
Immunogen Synthesized peptide derived from DBP . at AA range: 90-170
Specificity DBP Polyclonal Antibody detects endogenous levels of DBP protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name GC
Accession No. P02774 P21614
Alternate Names GC; Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component
Description GC, vitamin D binding protein(GC) Homo sapiens The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011],
Subcellular Localization extracellular region,extracellular space,cytosol,lysosomal lumen,extracellular exosome,blood microparticle,
Protein Function function:Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.,polymorphism:Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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