ITT1297
ITT1297
- Catalog: ITT1297
- Gene/Protein: GC
- Product Description: Immunotag™ DBP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | DBP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Monkey |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from DBP . at AA range: 90-170 |
| Specificity | DBP Polyclonal Antibody detects endogenous levels of DBP protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GC |
| Accession No. | P02774 P21614 |
| Alternate Names | GC; Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component |
| Description | GC, vitamin D binding protein(GC) Homo sapiens The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011], |
| Subcellular Localization | extracellular region,extracellular space,cytosol,lysosomal lumen,extracellular exosome,blood microparticle, |
| Protein Function | function:Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.,polymorphism:Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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