ITT1478
ITT1478
- Catalog: ITT1478
- Gene/Protein: TRIM25
- Product Description: Immunotag™ EFP Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | EFP |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF147. AA range:201-250 |
Specificity | EFP Polyclonal Antibody detects endogenous levels of EFP protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TRIM25 |
Accession No. | Q14258 Q61510 |
Alternate Names | TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147 |
Description | tripartite motif containing 25(TRIM25) Homo sapiens The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | RIG-I-like receptor, |
Protein Expression | Brain,Lymph,Placenta, |
Subcellular Localization | nucleoplasm,cytoplasm,cytosol,cell-cell adherens junction, |
Protein Function | function:Mediates estrogen action in various target organs.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Ubiquitous., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |