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ITT1479

ITT1479
  • Gene/Protein: TUFM
  • Product Description: Immunotag™ EF-Tu Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ EF-Tu Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein EF-Tu
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from EF-Tu, at AA range: 270-350
Specificity EF-Tu Polyclonal Antibody detects endogenous levels of EF-Tu protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TUFM
Accession No. P49411 Q8BFR5 P85834
Alternate Names TUFM; Elongation factor Tu; mitochondrial; EF-Tu; P43
Description Tu translation elongation factor, mitochondrial(TUFM) Homo sapiens This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Cajal-Retzius cell,Heart,Kidney,Liver,Lung,Placenta,P
Subcellular Localization mitochondrion,mitochondrial inner membrane,membrane,mitochondrial nucleoid,myelin sheath,extracellular exosome,
Protein Function disease:Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4) [MIM:610678]. COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.,function:This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.,similarity:Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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