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ITT1617

ITT1617
  • Gene/Protein: ERF
  • Product Description: Immunotag™ ERF Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ ERF Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ERF
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human ERF. AA range:471-520
Specificity ERF Polyclonal Antibody detects endogenous levels of ERF protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name ERF
Accession No. P50548 P70459
Alternate Names ERF; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE-2
Description ETS2 repressor factor(ERF) Homo sapiens ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
Protein Expression Brain,Duodenum,Epithelium,
Subcellular Localization nucleus,nucleoplasm,Golgi apparatus,cytosol,
Protein Function function:Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation.,PTM:Phosphorylated by multiple kinases including probably ERK2. Phosphorylation regulates the activity of ERF.,sequence caution:The sequence differs from that shown because it seems to be derived from a pre-mRNA.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,tissue specificity:Highest levels in testis, ovary, pancreas, and heart.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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