ITT1819
ITT1819
- Catalog: ITT1819
- Gene/Protein: SLC6A1
- Product Description: Immunotag™ GABA T-1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GABA T-1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from GABA T-1, at AA range: 350-430 |
Specificity | GABA T-1 Polyclonal Antibody detects endogenous levels of GABA T-1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SLC6A1 |
Accession No. | P30531 P31648 P23978 |
Alternate Names | SLC6A1; GABATR; GABT1; GAT1; Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1 |
Description | solute carrier family 6 member 1(SLC6A1) Homo sapiens The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009], |
Protein Expression | Brain, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,cell surface,membrane,integral component of membrane,axon,neuron projection, |
Protein Function | domain:The PDZ domain-binding motif is involved in the interaction with MPP5.,function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subcellular location:Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.,subunit:Interacts with MPP5., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |