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ITT1833

ITT1833
ITT1833-2
ITT1833
ITT1833-2
ITT1833
  • Catalog: ITT1833
  • Gene/Protein: GRAP2
  • Product Description: Immunotag™ Gads Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ Gads Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Gads
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human GRAP2. AA range:121-170
Specificity Gads Polyclonal Antibody detects endogenous levels of Gads protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name GRAP2
Accession No. O75791 O89100
Alternate Names GRAP2; GADS; GRB2L; GRID; GRB2-related adapter protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein Grp
Description GRB2-related adaptor protein 2(GRAP2) Homo sapiens This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
Cell Pathway/ Category T_Cell_Receptor,
Protein Expression Blood,Lung,Platelet,Spleen,T-cell,Thymus,
Subcellular Localization nucleus,nucleoplasm,cytoplasm,endosome,cytosol,
Protein Function function:Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.,similarity:Belongs to the GRB2/sem-5/DRK family.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with phosphorylated LIME1 upon TCR activation (By similarity). Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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