ITT1854
ITT1854
- Catalog: ITT1854
- Gene/Protein: GAS8
- Product Description: Immunotag™ Gas8 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Gas8 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,WB,ELISA |
| Recommended Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human Gas8 |
| Specificity | Gas8 Polyclonal Antibody detects endogenous levels of Gas8 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GAS8 |
| Accession No. | O95995 Q60779 Q499U4 |
| Alternate Names | GAS8; GAS11; Growth arrest-specific protein 8; GAS-8; Growth arrest-specific protein 11; GAS-11 |
| Description | growth arrest specific 8(GAS8) Homo sapiens This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013], |
| Protein Expression | Brain,Rectum tumor, |
| Subcellular Localization | Golgi apparatus,microtubule,cilium,axoneme,motile cilium,ciliary basal body, |
| Protein Function | disease:Defects in GAS8 may be a cause of infertility in male lacking gametocytes.,function:Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility.,similarity:Belongs to the GAS8 family.,subcellular location:Associates with microtubules (By similarity). Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa.,tissue specificity:Expressed in the heart, skeletal muscle, pancreas and liver. Weakly or not expressed in brain, placenta, lung and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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