ITT1856
ITT1856
- Catalog: ITT1856
- Gene/Protein: GPRASP1
- Product Description: Immunotag™ GASP-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GASP-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,IF,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790 |
| Specificity | GASP-1 Polyclonal Antibody detects endogenous levels of GASP-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GPRASP1 |
| Accession No. | Q5JY77 Q5U4C1 |
| Alternate Names | GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1 |
| Description | G protein-coupled receptor associated sorting protein 1(GPRASP1) Homo sapiens This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010], |
| Protein Expression | Brain,Heart, |
| Subcellular Localization | cytoplasm, |
| Protein Function | function:May modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes.,similarity:Belongs to the GPRASP family.,subunit:Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as D2 dopamine receptor/DRD2 (By similarity), delta opioid receptor/OPRD1, beta-2 adrenergic receptor/ADRB2 and D4 dopamine receptor/DRD4. Interacts with PER1.,tissue specificity:Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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