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ITT1906

ITT1906
ITT1906
  • Gene/Protein: GIPR
  • Product Description: Immunotag™ GIPR Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT1906

Immunotag™ GIPR Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GIPR
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human GIPR. AA range:93-142
Specificity GIPR Polyclonal Antibody detects endogenous levels of GIPR protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name GIPR
Accession No. P48546 Q0P543
Alternate Names GIPR; Gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor
Description gastric inhibitory polypeptide receptor(GIPR) Homo sapiens This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011],
Cell Pathway/ Category Neuroactive ligand-receptor interaction,
Protein Expression Colon,G-protein coupled receptors,Pancreas,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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