ITT1952
ITT1952
- Catalog: ITT1952
- Gene/Protein: P2RY14
- Product Description: Immunotag™ GPR105 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GPR105 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from GPR105, at AA range: 120-200 |
Specificity | GPR105 Polyclonal Antibody detects endogenous levels of GPR105 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | P2RY14 |
Accession No. | Q15391 Q9ESG6 O35881 |
Alternate Names | P2RY14; GPR105; KIAA0001; P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor |
Description | purinergic receptor P2Y14(P2RY14) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Amygdala,Bone marrow,Heart,Testis, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
Protein Function | function:Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |