ITT2097
ITT2097
- Catalog: ITT2097
- Gene/Protein: GNG5
- Product Description: Immunotag™ Gγ 5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Gγ 5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IF,ELISA |
| Recommended Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Gγ 5, at AA range: 10-90 |
| Specificity | Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GNG5 |
| Accession No. | P63218 Q80SZ7 P63219 |
| Alternate Names | GNG5; GNGT5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| Description | G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010], |
| Cell Pathway/ Category | Chemokine, |
| Protein Expression | Brain,Platelet,Umbilical cord blood, |
| Subcellular Localization | mitochondrion,heterotrimeric G-protein complex,plasma membrane,membrane,G-protein beta/gamma-subunit complex,extracellular exosome, |
| Protein Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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