ITT2122
ITT2122
- Catalog: ITT2122
- Gene/Protein: CCNB1IP1
- Product Description: Immunotag™ HEI10 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HEI10 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CCNB1IP1. AA range:201-250 |
| Specificity | HEI10 Polyclonal Antibody detects endogenous levels of HEI10 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CCNB1IP1 |
| Accession No. | Q9NPC3 |
| Alternate Names | CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10 |
| Description | cyclin B1 interacting protein 1(CCNB1IP1) Homo sapiens HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004], |
| Protein Expression | Brain,Cervix carcinoma,Fetal brain,Lung,Muscle,Placenta,Small intes |
| Subcellular Localization | synaptonemal complex, |
| Protein Function | function:E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated by CDC2 on serine or threonine residues (in vitro).,PTM:Ubiquitinated; autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,subcellular location:May associate with segregating chromosomes during metaphase and anaphase.,subunit:Binds CCNB1 and UBE2L3.,tissue specificity:Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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