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ITT2122

ITT2122
ITT2122
ITT2122
  • Gene/Protein: CCNB1IP1
  • Product Description: Immunotag™ HEI10 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ HEI10 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein HEI10
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human CCNB1IP1. AA range:201-250
Specificity HEI10 Polyclonal Antibody detects endogenous levels of HEI10 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CCNB1IP1
Accession No. Q9NPC3
Alternate Names CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10
Description cyclin B1 interacting protein 1(CCNB1IP1) Homo sapiens HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004],
Protein Expression Brain,Cervix carcinoma,Fetal brain,Lung,Muscle,Placenta,Small intes
Subcellular Localization synaptonemal complex,
Protein Function function:E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated by CDC2 on serine or threonine residues (in vitro).,PTM:Ubiquitinated; autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,subcellular location:May associate with segregating chromosomes during metaphase and anaphase.,subunit:Binds CCNB1 and UBE2L3.,tissue specificity:Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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