ITT2314
ITT2314
- Catalog: ITT2314
- Gene/Protein: IL13RA2
- Product Description: Immunotag™ IL-13Rα2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | IL-13Rα2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human IL13RA2. AA range:315-364 |
Specificity | IL-13Rα2 Polyclonal Antibody detects endogenous levels of IL-13Rα2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | IL13RA2 |
Accession No. | Q14627 O88786 |
Alternate Names | IL13RA2; IL13R; Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; Interleukin-13-binding protein; CD antigen CD213a2 |
Description | interleukin 13 receptor subunit alpha 2(IL13RA2) Homo sapiens The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Jak_STAT, |
Protein Expression | Brain,Lung,Prostate,Renal cell carcinoma,Testis, |
Subcellular Localization | extracellular region,extracellular space,membrane,integral component of membrane, |
Protein Function | domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Binds as a monomer with high affinity to interleukin 13 (IL13), but not to IL4.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,similarity:Contains 1 fibronectin type-III domain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |