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ITT2314

ITT2314
  • Catalog: ITT2314
  • Gene/Protein: IL13RA2
  • Product Description: Immunotag™ IL-13Rα2 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ IL-13Rα2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein IL-13Rα2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human IL13RA2. AA range:315-364
Specificity IL-13Rα2 Polyclonal Antibody detects endogenous levels of IL-13Rα2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name IL13RA2
Accession No. Q14627 O88786
Alternate Names IL13RA2; IL13R; Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; Interleukin-13-binding protein; CD antigen CD213a2
Description interleukin 13 receptor subunit alpha 2(IL13RA2) Homo sapiens The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Jak_STAT,
Protein Expression Brain,Lung,Prostate,Renal cell carcinoma,Testis,
Subcellular Localization extracellular region,extracellular space,membrane,integral component of membrane,
Protein Function domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Binds as a monomer with high affinity to interleukin 13 (IL13), but not to IL4.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,similarity:Contains 1 fibronectin type-III domain.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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