ITT2349
ITT2349
- Catalog: ITT2349
- Gene/Protein: INHBB
- Product Description: Immunotag™ Inhibin β-B Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Inhibin β-B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from the Internal region of human Inhibin β-B |
Specificity | Inhibin β-B Polyclonal Antibody detects endogenous levels of Inhibin β-B protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | INHBB |
Accession No. | P09529 Q04999 P17491 |
Alternate Names | INHBB; Inhibin beta B chain; Activin beta-B chain |
Description | inhibin beta B subunit(INHBB) Homo sapiens This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,TGF-beta, |
Protein Expression | Brain, |
Subcellular Localization | extracellular region,extracellular space,perinuclear region of cytoplasm,cell periphery, |
Protein Function | function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Inhibin entry,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |