ITT2379
ITT2379
- Catalog: ITT2379
- Gene/Protein: CXCL10
- Product Description: Immunotag™ IP-10 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | IP-10 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from IP-10 . at AA range: 20-100 |
Specificity | IP-10 Polyclonal Antibody detects endogenous levels of IP-10 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CXCL10 |
Accession No. | P02778 P17515 |
Alternate Names | CXCL10; INP10; SCYB10; C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10 |
Description | C-X-C motif chemokine ligand 10(CXCL10) Homo sapiens This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Chemokine,Toll_Like,RIG-I-like receptor,Cytosolic DNA-sensing pathway, |
Protein Expression | Foreskin keratinocyte,Keratinocyte,Prostate, |
Subcellular Localization | extracellular region,extracellular space,external side of plasma membrane, |
Protein Function | function:Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.,induction:By interferon gamma. A diverse population of cell types rapidly increases transcription of mRNA encoding this protein. This suggests that gamma-induced protein may be a key mediator of the interferon gamma response.,mass spectrometry: PubMed:11559369,online information:CXCL10 entry,PTM:CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |