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ITT2379

ITT2379
  • Catalog: ITT2379
  • Gene/Protein: CXCL10
  • Product Description: Immunotag™ IP-10 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ IP-10 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein IP-10
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from IP-10 . at AA range: 20-100
Specificity IP-10 Polyclonal Antibody detects endogenous levels of IP-10 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CXCL10
Accession No. P02778 P17515
Alternate Names CXCL10; INP10; SCYB10; C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10
Description C-X-C motif chemokine ligand 10(CXCL10) Homo sapiens This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014],
Cell Pathway/ Category Cytokine-cytokine receptor interaction,Chemokine,Toll_Like,RIG-I-like receptor,Cytosolic DNA-sensing pathway,
Protein Expression Foreskin keratinocyte,Keratinocyte,Prostate,
Subcellular Localization extracellular region,extracellular space,external side of plasma membrane,
Protein Function function:Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.,induction:By interferon gamma. A diverse population of cell types rapidly increases transcription of mRNA encoding this protein. This suggests that gamma-induced protein may be a key mediator of the interferon gamma response.,mass spectrometry: PubMed:11559369,online information:CXCL10 entry,PTM:CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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