ITT2386
ITT2386
- Catalog: ITT2386
- Gene/Protein: PPP1R2
- Product Description: Immunotag™ IPP-2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | IPP-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from IPP-2, at AA range: 60-140 |
Specificity | IPP-2 Polyclonal Antibody detects endogenous levels of IPP-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | PPP1R2 |
Accession No. | P41236 Q9DCL8 P50411 |
Alternate Names | PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2 |
Description | protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015], |
Protein Expression | Epithelium,Heart,Platelet,Skin,Testis, |
Subcellular Localization | protein phosphatase type 1 complex, |
Protein Function | function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |