ITT2450
ITT2450
- Catalog: ITT2450
- Gene/Protein: KANK2
- Product Description: Immunotag™ KANK2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | KANK2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human KANK2. AA range:351-400 |
Specificity | KANK2 Polyclonal Antibody detects endogenous levels of KANK2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | KANK2 |
Accession No. | Q63ZY3 Q8BX02 |
Alternate Names | KANK2; ANKRD25; KIAA1518; MXRA3; SIP; KN motif and ankyrin repeat domain-containing protein 2; Ankyrin repeat domain-containing protein 25; Matrix-remodeling-associated protein 3; SRC-1-interacting protein; SIP; SRC-interacting protein; SRC |
Description | KN motif and ankyrin repeat domains 2(KANK2) Homo sapiens This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016], |
Protein Expression | Adipose tissue,Cervix,Epithelium,Lung,Ovary,Placenta,Spleen,Testis, |
Subcellular Localization | cytoplasm,mitochondrion, |
Protein Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 5 ANK repeats.,tissue specificity:Strongly expressed in cervix, colon, heart, kidney and lung., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |