ITT2599
ITT2599
- Catalog: ITT2599
- Gene/Protein: CACNG1
- Product Description: Immunotag™ L-type Ca++ CP γ1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | L-type Ca++ CP γ1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from L-type Ca++ CP γ1, at AA range: 110-190 |
| Specificity | L-type Ca++ CP γ1 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CACNG1 |
| Accession No. | Q06432 O70578 P97707 |
| Alternate Names | CACNG1; CACNLG; Voltage-dependent calcium channel gamma-1 subunit; Dihydropyridine-sensitive L-type; skeletal muscle calcium channel subunit gamma |
| Description | calcium voltage-gated channel auxiliary subunit gamma 1(CACNG1) Homo sapiens Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Cardiac muscle contraction,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
| Protein Expression | Fetal skeletal muscle, |
| Subcellular Localization | plasma membrane,voltage-gated calcium channel complex, |
| Protein Function | function:This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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