ITT2609
ITT2609
- Catalog: ITT2609
- Gene/Protein: LYPLA1
- Product Description: Immunotag™ LYPLA1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | LYPLA1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from LYPLA1, at AA range: 30-110 |
Specificity | LYPLA1 Polyclonal Antibody detects endogenous levels of LYPLA1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | LYPLA1 |
Accession No. | O75608 P97823 P70470 |
Alternate Names | LYPLA1; APT1; LPL1; Acyl-protein thioesterase 1; APT-1; hAPT1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I |
Description | lysophospholipase I(LYPLA1) Homo sapiens This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013], |
Cell Pathway/ Category | Glycerophospholipid metabolism, |
Protein Expression | Bone marrow,Brain,Eye,Testis,Umbilical cord blood, |
Subcellular Localization | cytoplasm,mitochondrion,cytosol,integral component of membrane,extracellular exosome, |
Protein Function | catalytic activity:Palmitoyl-protein + H(2)O = palmitate + protein.,function:Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Also has low lysophospholipase activity.,similarity:Belongs to the AB hydrolase 2 family.,subunit:Homodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |