ITT2676
ITT2676
- Catalog: ITT2676
- Gene/Protein: MC5R
- Product Description: Immunotag™ MC5-R Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MC5-R |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from MC5-R, at AA range: 240-320 |
Specificity | MC5-R Polyclonal Antibody detects endogenous levels of MC5-R protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MC5R |
Accession No. | P33032 P41149 P35345 |
Alternate Names | MC5R; Melanocortin receptor 5; MC5-R; MC-2 |
Description | melanocortin 5 receptor(MC5R) Homo sapiens This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Placenta, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
Protein Function | function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in the brain but not in the melanoma cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |