ITT3066
ITT3066
- Catalog: ITT3066
- Gene/Protein: CSPG5
- Product Description: Immunotag™ Neuroglycan C Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Neuroglycan C |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Neuroglycan C, at AA range: 180-260 |
Specificity | Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CSPG5 |
Accession No. | O95196 Q71M36 Q9ERQ6 |
Alternate Names | CSPG5; CALEB; NGC; Chondroitin sulfate proteoglycan 5; Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C |
Description | chondroitin sulfate proteoglycan 5(CSPG5) Homo sapiens The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011], |
Protein Expression | Brain, |
Subcellular Localization | Golgi membrane,extracellular region,endoplasmic reticulum membrane,Golgi apparatus,Golgi lumen,integral component of plasma membrane,cell surface,membrane,integral component of membrane,Golgi-associated vesicle membrane,lys |
Protein Function | developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals.,function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.,miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage.,PTM:N-glycosylated.,PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.,PTM:Phosphorylated; in intracellular and extracellular parts.,similarity:Contains 1 EGF-like domain.,subcellular location:In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reticulum and the Golgi (By similarity). Partially enriched in lipid rafts.,subunit:Binds TNR and probably TNC (By similarity). Interacts with ERBB3 and GOPC.,tissue specificity:Restricted to brain (at protein level)., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |