ITT3068
ITT3068
- Catalog: ITT3068
- Gene/Protein: NMU
- Product Description: Immunotag™ Neuromedin-U Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Neuromedin-U |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human NMU. AA range:125-174 |
Specificity | Neuromedin-U Polyclonal Antibody detects endogenous levels of Neuromedin-U protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NMU |
Accession No. | P48645 Q9QXK8 |
Alternate Names | NMU; Neuromedin-U |
Description | neuromedin U(NMU) Homo sapiens This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015], |
Protein Expression | Brain,Ovary,Pituitary, |
Subcellular Localization | extracellular region,terminal bouton, |
Protein Function | function:Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.,similarity:Belongs to the NmU family.,tissue specificity:Expressed throughout the enteric nervous system with highest levels being found in the jejunum., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |