ITT3078
ITT3078
- Catalog: ITT3078
- Gene/Protein: NFIA
- Product Description: Immunotag™ NF-1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NF1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from NF-1, at AA range: 30-110 |
Specificity | NF-1 Polyclonal Antibody detects endogenous levels of NF-1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NFIA |
Accession No. | Q12857/O00712/P08651/Q14938 P09414 |
Alternate Names | NFIA; KIAA1439; Nuclear factor 1 A-type; NF1-A; Nuclear factor 1/A; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein; NFIB; Nuclear factor 1 B-type; NF1-B; Nuclear factor 1/B; CCAAT-box-b |
Description | nuclear factor I A(NFIA) Homo sapiens This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011], |
Protein Expression | Brain,Epithelium,Skeletal muscle,Testis, |
Subcellular Localization | nucleus,nucleoplasm,cell junction, |
Protein Function | function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |