menu
Your Cart

ITT3167

  • Gene/Protein: NR4A3
  • Product Description: Immunotag™ NOR-1 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT3167

Immunotag™ NOR-1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NOR-1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from NOR-1, at AA range: 360-440
Specificity NOR-1 Polyclonal Antibody detects endogenous levels of NOR-1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name NR4A3
Accession No. Q92570 Q9QZB6 P51179
Alternate Names NR4A3; CHN; CSMF; MINOR; NOR1; TEC; Nuclear receptor subfamily 4 group A member 3; Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1
Description nuclear receptor subfamily 4 group A member 3(NR4A3) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Protein Expression Fetal brain,Fetal heart,Liver,Peripheral blood,Skeletal mus
Subcellular Localization nucleus,nucleoplasm,transcription factor complex,mast cell granule,
Protein Function disease:A chromosomal aberration involving NR4A3 is a cause of a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with TAF2N.,disease:A chromosomal aberration involving NR4A3 is a cause of Ewing sarcoma [MIM:133450]. Translocation t(9;22)(q22-31;q11-12) with EWS.,function:Binds to the B1A response-element.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR4 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,tissue specificity:High expression of isoform alpha in skeletal muscle. High expression of isoform beta in skeletal muscle and low expression in fetal brain and placenta.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Norwegian
Portuguese
Finnish
Swedish
Polish
Write a review
Note: HTML is not translated!
Bad Good
Captcha

Latest Blog

Download our handbooks

Custom Services

Connect With Us

Stay up to date with G-Biosciences by signing up for our newsletter.