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ITT3182

ITT3182
  • Gene/Protein: NPY
  • Product Description: Immunotag™ NPY Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ NPY Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NPY
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human NPY
Specificity NPY Polyclonal Antibody detects endogenous levels of NPY protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name NPY
Accession No. P01303 P57774 P07808
Alternate Names NPY; Pro-neuropeptide Y
Description neuropeptide Y(NPY) Homo sapiens This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],
Cell Pathway/ Category Adipocytokine,
Protein Expression Brain,Hippocampus,
Subcellular Localization extracellular region,extracellular space,cell,Golgi apparatus,
Protein Function function:NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.,online information:Neuropeptide Y entry,similarity:Belongs to the NPY family.,tissue specificity:One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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