ITT3612
ITT3612
- Catalog: ITT3612
- Gene/Protein: TSPO
- Product Description: Immunotag™ PBR Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PBR |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from PBR . at AA range: 90-170 |
| Specificity | PBR Polyclonal Antibody detects endogenous levels of PBR protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TSPO |
| Accession No. | P30536 |
| Alternate Names | TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR |
| Description | translocator protein(TSPO) Homo sapiens Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Placenta, |
| Subcellular Localization | cytoplasm,mitochondrion,mitochondrial outer membrane,integral component of membrane,nuclear membrane,intracellular membrane-bounded organelle,extracellular exosome, |
| Protein Function | protein targeting, protein targeting to mitochondrion, porphyrin metabolic process, porphyrin biosynthetic process,heme biosynthetic process, ion transport, anion transport, mitochondrial transport, intracellular protein transport,apoptosis, mitochondrion organization, protein localization, steroid metabolic process, cell death, cell proliferation,programmed cell death, protein transport, death, protein import, heterocycle biosynthetic process, regulation of lipid transport, regulation of sterol transport, regulation of cholesterol transport, tetrapyrrole metabolic process,tetrapyrrole biosynthetic process, protein localization in organelle, cellular protein localization, heme metabolic process, pigment metabolic process, nitrogen compound biosynthetic process, establishment of protein localization,pigment biosynthetic process, intracellular transport, cofactor metabolic process, cofactor biosynthetic process, protein localization in mitochondrion, cellular macromolecule localization, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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