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ITT3620

ITT3620
  • Catalog: ITT3620
  • Gene/Protein: PLD2
  • Product Description: Immunotag™ PC-PLD2 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PC-PLD2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PC-PLD2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from PC-PLD2, at AA range: 110-190
Specificity PC-PLD2 Polyclonal Antibody detects endogenous levels of PC-PLD2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PLD2
Accession No. O14939 P97813 P70498
Alternate Names PLD2; Phospholipase D2; PLD 2; hPLD2; Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2
Description phospholipase D2(PLD2) Homo sapiens The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011],
Cell Pathway/ Category Glycerophospholipid metabolism,Ether lipid metabolism,Endocytosis,Fc gamma R-mediated phagocytosis,GnRH,
Protein Expression B-cell,Brain,Skin,Uterus,
Subcellular Localization intracellular,endoplasmic reticulum membrane,Golgi apparatus,plasma membrane,presynapse,
Protein Function catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,enzyme regulation:Stimulated by phosphatidylinositol 4,5-bisphosphate and activated by the ADP-ribosylation factor-1 (ARF-1).,function:May have a role in signal-induced cytoskeletal regulation and/or endocytosis.,online information:Phospholipase D entry,similarity:Belongs to the phospholipase D family.,similarity:Contains 1 PH domain.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 PLD phosphodiesterase domains.,subunit:Interacts with EGFR (By similarity). Interacts with PIP5K1A.,tissue specificity:Ubiquitous.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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