ITT3621
ITT3621
- Catalog: ITT3621
- Gene/Protein: PLD3
- Product Description: Immunotag™ PC-PLD3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PC-PLD3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from PC-PLD3, at AA range: 300-380 |
| Specificity | PC-PLD3 Polyclonal Antibody detects endogenous levels of PC-PLD3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PLD3 |
| Accession No. | Q8IV08 O35405 Q5FVH2 |
| Alternate Names | PLD3; Phospholipase D3; PLD 3; Choline phosphatase 3; HindIII K4L homolog; Hu-K4; Phosphatidylcholine-hydrolyzing phospholipase D3 |
| Description | phospholipase D family member 3(PLD3) Homo sapiens This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014], |
| Protein Expression | Brain,Colon,Liver,Lung,Mammary gland, |
| Subcellular Localization | endoplasmic reticulum membrane,integral component of membrane,extracellular exosome, |
| Protein Function | catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,PTM:Glycosylated.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,tissue specificity:Widely expressed. Expressec at higher level in brain. Expresse at low level in corpus callosum, suggsting that it is highly expressed in neurons., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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