ITT3819
ITT3819
- Catalog: ITT3819
- Gene/Protein: POM121
- Product Description: Immunotag™ POM121 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | POM121 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from POM121, at AA range: 1170-1250 |
| Specificity | POM121 Polyclonal Antibody detects endogenous levels of POM121 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | POM121 |
| Accession No. | Q96HA1/A6NF01/A8CG34 P52591 |
| Alternate Names | POM121; KIAA0618; NUP121; POM121A; Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; Nucleoporin Nup121; Pore membrane protein of 121 kDa; POM121B; Putative nuclear envelope pore membrane prote |
| Description | POM121 transmembrane nucleoporin(POM121) Homo sapiens This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013], |
| Protein Expression | Brain,Cervix,Lymph,Skin,Teratocarcinoma,Testis,Uterus, |
| Subcellular Localization | nuclear envelope,nuclear pore,endoplasmic reticulum membrane,integral component of membrane,nuclear membrane,nuclear pore central transport channel,nuclear pore nuclear basket, |
| Protein Function | domain:Contains F-X-F-G repeats.,function:Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).,similarity:Belongs to the POM121 family.,subcellular location:Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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