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ITT3902

ITT3902
  • Catalog: ITT3902
  • Gene/Protein: PTPRA
  • Product Description: Immunotag™ PTPα Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PTPα Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PTPα
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from PTPα, at AA range: 730-810
Specificity PTPα Polyclonal Antibody detects endogenous levels of PTPα protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PTPRA
Accession No. P18433 P18052 Q03348
Alternate Names PTPRA; PTPA; PTPRL2; Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha
Description protein tyrosine phosphatase, receptor type A(PTPRA) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Epithelium,Kidney,Lymph node,Skin,
Subcellular Localization intracellular,plasma membrane,integral component of plasma membrane,integral component of membrane,receptor complex,extracellular exosome,
Protein Function catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.,similarity:Contains 2 tyrosine-protein phosphatase domains.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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