ITT3916
ITT3916
- Catalog: ITT3916
- Gene/Protein: RPL10
- Product Description: Immunotag™ QM Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | QM |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from QM, at AA range: 10-90 |
| Specificity | QM Polyclonal Antibody detects endogenous levels of QM protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RPL10 |
| Accession No. | P27635 Q6ZWV3 Q6PDV7 |
| Alternate Names | RPL10; DXS648E; QM; 60S ribosomal protein L10; Laminin receptor homolog; Protein QM; Tumor suppressor QM |
| Description | ribosomal protein L10(RPL10) Homo sapiens This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
| Cell Pathway/ Category | Ribosome, |
| Protein Expression | Brain,Human lung,Mammary cancer,Mammary gland,Ovarian carcinoma,Pancreatic cancer,P |
| Subcellular Localization | endoplasmic reticulum,cytosol,ribosome,membrane,cytosolic large ribosomal subunit, |
| Protein Function | developmental stage:Down-regulated during adipocyte, kidney, and heart differentiation.,disease:Defects in RPL10 may be the cause of susceptibility to X-linked autism [MIM:209850]. Autism is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.,similarity:Belongs to the ribosomal protein L10e family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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