ITT4058
ITT4058
- Catalog: ITT4058
- Gene/Protein: NR1D1
- Product Description: Immunotag™ Rev-erbα Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | REV-erbα |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Rev-erbα . at AA range: 350-430 |
| Specificity | Rev-erbα Polyclonal Antibody detects endogenous levels of Rev-erbα protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NR1D1 |
| Accession No. | P20393 Q3UV55 |
| Alternate Names | NR1D1; EAR1; HREV; THRAL; Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1; EAR-1 |
| Description | nuclear receptor subfamily 1 group D member 1(NR1D1) Homo sapiens This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013], |
| Cell Pathway/ Category | Circadian rhythm, |
| Protein Expression | Epithelium,Fetal skeletal muscle,Placenta,PNS, |
| Subcellular Localization | nuclear chromatin,nucleus,nucleoplasm,cytoplasm,dendrite,dendritic spine, |
| Protein Function | domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with C1D.,tissue specificity:Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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