ITT4145
ITT4145
- Catalog: ITT4145
- Gene/Protein: RIN3
- Product Description: Immunotag™ RIN3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | RIN3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RIN3. AA range:391-440 |
| Specificity | RIN3 Polyclonal Antibody detects endogenous levels of RIN3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RIN3 |
| Accession No. | Q8TB24 P59729 |
| Alternate Names | RIN3; Ras and Rab interactor 3; Ras interaction/interference protein 3 |
| Description | Ras and Rab interactor 3(RIN3) Homo sapiens Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], |
| Protein Expression | Embryo,Eye,Fetal liver,Leukocyte,Melanoma,Placenta,Spleen,Thymus, |
| Subcellular Localization | early endosome,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle, |
| Protein Function | caution:The region from Asp-168 to Pro-327 is deduced from the genomic sequence by similarity to the mouse sequence.,function:Potential Ras effector protein. May function as a guanine nucleotide exchange (GEF), by exchanging bound GDP for free GTP.,similarity:Belongs to the RIN (Ras interaction/interference) family.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 VPS9 domain.,subcellular location:Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles.,subunit:Interacts with RAB5B and BIN1.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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