ITT4259
ITT4259
- Catalog: ITT4259
- Gene/Protein: SERPINA6
- Product Description: Immunotag™ SerpinA6 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SERPINA6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human SerpinA6. |
| Specificity | SerpinA6 Polyclonal Antibody detects endogenous levels of SerpinA6 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SERPINA6 |
| Accession No. | P08185 Q06770 |
| Alternate Names | SERPINA6; CBG; Corticosteroid-binding globulin; CBG; Serpin A6; Transcortin |
| Description | serpin family A member 6(SERPINA6) Homo sapiens This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008], |
| Protein Expression | Liver,Lung,Plasma, |
| Subcellular Localization | extracellular space,extracellular exosome, |
| Protein Function | disease:Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.,function:Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.,online information:Transcortin entry,PTM:Glycosylation in position Asn-260 is needed for steroid binding.,PTM:N-glycosylated; binds 5 oligosaccharide chains.,similarity:Belongs to the serpin family.,tissue specificity:Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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