ITT4274
ITT4274
- Catalog: ITT4274
- Gene/Protein: SLC5A2
- Product Description: Immunotag™ SGLT-2 Polyclonal Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | SGLT-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from SGLT-2, at AA range: 70-150 |
Specificity | SGLT-2 Polyclonal Antibody detects endogenous levels of SGLT-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SLC5A2 |
Accession No. | P31639 Q923I7 P53792 |
Alternate Names | SLC5A2; SGLT2; Sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2 |
Description | solute carrier family 5 member 2(SLC5A2) Homo sapiens This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015], |
Protein Expression | Kidney, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane,extracellular exosome, |
Protein Function | disease:Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.,function:Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.,function:Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |