ITT4430
ITT4430
- Catalog: ITT4430
- Gene/Protein: SSTR4
- Product Description: Immunotag™ SSTR4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SSTR4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from SSTR4, at AA range: 130-210 |
Specificity | SSTR4 Polyclonal Antibody detects endogenous levels of SSTR4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SSTR4 |
Accession No. | P31391 P49660 P30937 |
Alternate Names | SSTR4; Somatostatin receptor type 4; SS-4-R; SS4-R; SS4R |
Description | somatostatin receptor 4(SSTR4) Homo sapiens Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,neuron projection, |
Protein Function | function:Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |