ITT4490
ITT4490
- Catalog: ITT4490
- Gene/Protein: SDC2
- Product Description: Immunotag™ Syndecan-2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Syndecan-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130 |
Specificity | Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SDC2 |
Accession No. | P34741 P43407 |
Alternate Names | SDC2; HSPG1; Syndecan-2; SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD antigen CD362 |
Description | syndecan 2(SDC2) Homo sapiens The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | ECM-receptor interaction,Cell adhesion molecules (CAMs), |
Protein Expression | Brain,Embryo,Lung fibroblast,Muscle,Testis, |
Subcellular Localization | Golgi lumen,plasma membrane,cell surface,integral component of membrane,lysosomal lumen, |
Protein Function | function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |