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ITT4505

  • Gene/Protein: TAS2R13
  • Product Description: Immunotag™ T2R13 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITT4505

Immunotag™ T2R13 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein T2R13
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TAS2R13. AA range:123-172
Specificity T2R13 Polyclonal Antibody detects endogenous levels of T2R13 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TAS2R13
Accession No. Q9NYV9 Q7M720
Alternate Names TAS2R13; Taste receptor type 2 member 13; T2R13; Taste receptor family B member 3; TRB3
Description taste 2 receptor member 13(TAS2R13) Homo sapiens This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Taste transduction,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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