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ITT4514

ITT4514
  • Gene/Protein: TAS2R5
  • Product Description: Immunotag™ T2R5 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ T2R5 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein T2R5
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TAS2R5. AA range:178-227
Specificity T2R5 Polyclonal Antibody detects endogenous levels of T2R5 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TAS2R5
Accession No. Q9NYW4
Alternate Names TAS2R5; Taste receptor type 2 member 5; T2R5
Description taste 2 receptor member 5(TAS2R5) Homo sapiens This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Taste transduction,
Protein Expression Brain,G-protein coupled receptors,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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