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ITT4531

ITT4531
ITT4531
ITT4531
  • Gene/Protein: TAF5L
  • Product Description: Immunotag™ TAF5L Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ TAF5L Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TAF5L
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Monkey
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TAF5L. AA range:291-340
Specificity TAF5L Polyclonal Antibody detects endogenous levels of TAF5L protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TAF5L
Accession No. O75529 Q91WQ5
Alternate Names TAF5L; PAF65B; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PCAF-associated factor 65 beta; PAF65-beta
Description TATA-box binding protein associated factor 5 like(TAF5L) Homo sapiens The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Basal transcription factors,
Protein Expression Brain,Eye,
Subcellular Localization STAGA complex,transcription factor TFTC complex,
Protein Function function:Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.,similarity:Belongs to the WD repeat TAF5 family.,similarity:Contains 6 WD repeats.,subunit:The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5, TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and SPT3. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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