ITT4539
ITT4539
- Catalog: ITT4539
- Gene/Protein: KCNK17
- Product Description: Immunotag™ TALK-2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TALK-2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320 |
| Specificity | TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | KCNK17 |
| Accession No. | Q96T54 |
| Alternate Names | KCNK17; TALK2; TASK4; Potassium channel subfamily K member 17; 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel |
| Description | potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008], |
| Protein Expression | Adrenal gland,Lung,Pancreas,Spleen, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer ., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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