ITT4573
ITT4573
- Catalog: ITT4573
- Gene/Protein: TCEAL1
- Product Description: Immunotag™ TCEAL1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TCEAL1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000.IHC-p:1:50-300 ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from TCEAL1, at AA range: 60-140 |
Specificity | TCEAL1 Polyclonal Antibody detects endogenous levels of TCEAL1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TCEAL1 |
Accession No. | Q15170 Q921P9 Q5PPP3 |
Alternate Names | TCEAL1; SIIR; Transcription elongation factor A protein-like 1; TCEA-like protein 1; Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1 |
Description | transcription elongation factor A like 1(TCEAL1) Homo sapiens This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008], |
Protein Expression | Placenta, |
Subcellular Localization | nucleus,nucleoplasm, |
Protein Function | function:May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.,PTM:Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.,similarity:Belongs to the TFS-II family. TFA subfamily.,tissue specificity:Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |