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ITT4646

ITT4646
ITT4646
ITT4646
  • Gene/Protein: THBS4
  • Product Description: Immunotag™ Thrombospondin 4 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ Thrombospondin 4 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Thrombospondin 4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human THBS4. AA range:561-610
Specificity Thrombospondin 4 Polyclonal Antibody detects endogenous levels of Thrombospondin 4 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name THBS4
Accession No. P35443 Q9Z1T2
Alternate Names THBS4; TSP4; Thrombospondin-4
Description thrombospondin 4(THBS4) Homo sapiens The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Cell Pathway/ Category TGF-beta,Focal adhesion,ECM-receptor interaction,
Protein Expression Heart,PNS,Synovium,
Subcellular Localization extracellular region,basement membrane,extracellular space,endoplasmic reticulum,sarcoplasmic reticulum,extracellular matrix,extracellular exosome,
Protein Function function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 4 EGF-like domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Homopentamer; disulfide-linked.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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