ITT4747
ITT4747
- Catalog: ITT4747
- Gene/Protein: TNNI3
- Product Description: Immunotag™ Troponin I-C Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Troponin I-C |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Troponin I-C, at AA range: 1-80 |
Specificity | Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TNNI3 |
Accession No. | P23693 |
Alternate Names | TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
Description | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |