ITT4786
ITT4786
- Catalog: ITT4786
- Gene/Protein: KCNK1
- Product Description: Immunotag™ TWIK-1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TWIK-1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336 |
Specificity | TWIK-1 Polyclonal Antibody detects endogenous levels of TWIK-1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | KCNK1 |
Accession No. | O00180 O08581 Q9Z2T2 |
Alternate Names | KCNK1; HOHO1; KCNO1; TWIK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1 |
Description | potassium two pore domain channel subfamily K member 1(KCNK1) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Kidney, |
Subcellular Localization | endosome,plasma membrane,integral component of plasma membrane,voltage-gated potassium channel complex,integral component of membrane,cytoplasmic, membrane-bounded vesicle,apical plasma membrane,cell junction,dendrite, |
Protein Function | function:Weakly inward rectifying potassium channel.,miscellaneous:Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |