ITT4802
ITT4802
- Catalog: ITT4802
- Gene/Protein: UBE3C
- Product Description: Immunotag™ UBE3C Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | UBE3C |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human UBE3C. |
| Specificity | UBE3C Polyclonal Antibody detects endogenous levels of UBE3C protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | UBE3C |
| Accession No. | Q15386 Q80U95 |
| Alternate Names | UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2 |
| Description | function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.,miscellaneous:A cysteine residue is required for ubiquitin-thioester formation.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas., |
| Cell Pathway/ Category | Ubiquitin mediated proteolysis, |
| Protein Expression | Bone marrow,Lung,Placenta, |
| Subcellular Localization | proteasome complex,intracellular,nucleus,cytoplasm, |
| Protein Function | function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.,miscellaneous:A cysteine residue is required for ubiquitin-thioester formation.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|